MANAGEMENT OF TRAUMATIC EVENTS: INFLUENCE OF EMOTION-CENTERED COPING STRATEGIES ON THE OCCURRENCE OF DISSOCIATION AND POST-TRAUMATIC STRESS DISORDER

Management of traumatic events: influence of emotion-centered coping strategies on the occurrence of dissociation and post-traumatic stress disorder

Georges Brousse1,2, Benjamin Arnaud1, Jordane Durand Roger1, Julie Geneste1, Delphine Bourguet1, Frederic Zaplana1, Olivier Blanc1, Jeannot Schmidt1,2, Louis Jehel31CHU Clermont Ferrand, Unité Urgences Psychiatriques, 28 place Henri Dunant BP 69, 63003 Clermont-Ferrand Cedex 01, France; 2Univ Clermont 1, UFR médecine, Clermont

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Hypoxia-altered cholesterol homeostasis enhances the expression of interferon-stimulated genes upon SARS-CoV-2 infections in monocytes

Hypoxia contributes to numerous pathophysiological conditions including inflammation-associated diseases.We characterized the impact of hypoxia on the immunometabolic cross-talk between cholesterol and interferon (IFN) responses.Specifically, hypoxia reduced cholesterol biosynthesis flux and provoked a compensatory activation of sterol regulatory e

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